Naloxone research

paperandpenWe've put this collection in the order that the research was released with the most recent first. Wherever possible we've linked to the full research article, however in some cases we have only linked to the abstract as the article itself is behind a paywall.

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Drug Death Database Report (Scotland)

on . Posted in Research

ISD Scotland have released the latest report from the National Drug Related Deaths Database (NDRDD) for Scotland which presents data for the calendar year 2012. The NDRDD was established to collect detailed information regarding the nature and social circumstances of individuals who have died a drug-related death.

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National Forum on Drug Related Deaths Report (Scotland)

on . Posted in Research

This report covers the work and activity during 2013. Already we are into a new year and the report of the Drug Deaths Database published along with this one will contain an exploratory account of new information on suicides and novel psychoactive substances.

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Implementing Expanding Naloxone Availability in the ACT (I-ENAACT) - Key Findings

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Key Interim Findings from the Independent evaluation of the ‘Implementing Expanding Naloxone Availability in the ACT (I-ENAACT)’ Program, 2011-2013 have been released. The ACT program provides comprehensive overdose management training and naloxone on prescription to be administered by trained peers or family members in the event of an opioid overdose.

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Drug-related deaths in the UK: January-December 2012

on . Posted in Research

This surveillance report presents information on drug-related deaths, both of addicts and non-addicts, that occurred during 2012 and for which Coronial inquests and similar formal investigations have been completed and information submitted. Its main purpose is to provide an analytical summary of data received, and through consistent surveillance to detect and identify emerging patterns and issues in respect of drug-related deaths. In this way, it contributes to the reduction and prevention of drug-related deaths in the UK due to the misuse of both licit and illicit drugs.

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Reducing drug related deaths: a pre-implementation assessment of knowledge,barriers and enablers for naloxone distribution through general practice

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The Scottish Naloxone Programme aims to reduce Scotland’s high number of drug-related deaths (DRDs) caused by opiate overdose. It is currently implemented through specialist drug services but General Practitioners (GPs) are likely to have contact with drug using patients and their families and are therefore in an ideal position to direct them to naloxone schemes, or provide it themselves. This research gathered baseline data on GP’s knowledge of and willingness to be involved in DRD prevention, including naloxone administration, prior to the implementation of primary care based delivery.

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Does take-home naloxone reduce non-fatal overdose?

on . Posted in Research

National data on the prevalence of non-fatal overdose in Wales are lacking. We designed a national survey of non-fatal overdose among injecting opiate users who attended needle-exchange schemes to create a baseline measure of the prevalence of non-fatal overdose that could be useful to monitor the impact of THN and other harm-reduction interventions. The survey, done in February and March 2013, included 661 respondents (48% of the 1380 opiate users registered in the needle exchange organisation's database). Among these 661 injecting opiate users, 308 had overdosed and 100 had overdosed in the past 12 months (similar to the 12% [39 out of 313] reported by Gossop and colleagues,3 in 1994). Of those who had overdosed in the past year, 85 disclosed how many times: once (44), two times (26), three (seven), four (two), five (two), six (one), seven (one), eight (one), and 12 times (one): a total of 168 survived overdoses. The mean was thus 2·0 (standard error 0·2) survived overdoses per respondent who had overdosed in the past year..

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Mortality due to opioid overdose found most often in prisoners post-release

on . Posted in Research

This study used information from the National Death Index to investigate mortality data in a population (n=76,208) of incarcerated individuals following their release from prison. The study was conducted across multiple prison facilities in Washington state from 1999 to 2009. Analysis revealed that individuals who had been incarcerated were 10.33 (95% CI: 8.61-11.10) times more likely to die from a pharmaceutical opioid overdose compared to control data from the CDC. Researchers also found that the overdose mortality rate in women was significantly higher than in men. Generalizability of this study may be limited by region as data was only analyzed on prisoners in the state of Washington. Furthermore, researchers were unable to determine whether pharmaceutical opioids were prescribed or obtained illicitly. However, the findings in this study still provide valuable data for policy makers and public health officials to better understand the unique health challenges of the incarcerated population.

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Drug-related deaths in Scotland in 2012

on . Posted in Research

Statistics of drug-related deaths in 2012 and earlier years, broken down by age, sex, selected drugs reported, underlying cause of death and NHS Board and Council areas.

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Drug Death Database Report (Scotland)

on . Posted in Research

ISD Scotland have released the third report from the National Drug Related Deaths Database (NDRDD) for Scotland which presents data for the calendar year 2011. The NDRDD was established to collect detailed information regarding the nature and social circumstances of individuals who have died a drug-related death.

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