Naloxone research

paperandpenWe've put this collection in the order that the research was released with the most recent first. Wherever possible we've linked to the full research article, however in some cases we have only linked to the abstract as the article itself is behind a paywall.

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Mortality among drug users in Europe: new and old challenges for public health

on . Posted in Research

This paper examines the overall number of lives lost due to drug use. All-cause mortality among problem drug users is investigated by means of cohort studies, which link data from death registries to drug treatment records. Building on earlier work, the paper presents data from nine European countries not previously studied using the same methodology. The study finds that the risk of death among problem drug users is typically 10 or more times that among their peers in the general population. The analysis shows that the deaths of problem drug users are overwhelmingly premature and preventable.

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5 Minutes Is All It Takes To Identify and Reverse an Overdose

on . Posted in Research

New evidence released today suggests that 5-10 minutes of education is all it takes to effectively recognize and respond to an overdose with the lifesaving drug naloxone. The findings, published in the journal Drug and Alcohol Dependence, contribute to a growing body of evidence that brief overdose education to opioid users is sufficient for effective naloxone distribution.

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New EMCDDA review studies the effectiveness of overdose antidote, naloxone

on . Posted in Research

Analysing 21 studies conducted in four countries — Canada, Germany, UK and the USA — today’s review examines the latest evidence on the role of take-home naloxone (THN) in reducing opioid overdose fatalities. It concludes that THN provision, delivered with educational and training interventions, can be effective in reducing overdose-related deaths and improving knowledge on the signs of overdose and the correct management of patients.

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Brief overdose education is sufficient for naloxone distribution to opioid users

on . Posted in Research

"Opioid users seeking naloxone in San Francisco have a high level of baseline knowledge around recognizing and responding to opioid overdose and those returning for refills retain that knowledge. Brief education is sufficient to improve comfort and facility in recognizing and managing overdose."

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Take-home naloxone (THN) & naloxone-on-release (NOR) reduce opioid-related deaths: from evidence of high risk soon after prison-release through science-led evaluations of THN/NOR to the monitoring of national naloxone policies.

on . Posted in Research

On December 8th 2014, we marked success. In 15 prisons in England, we ceased to randomize eligible prisoners (those with a history of heroin injection) in the N-ALIVE pilot Trial and, as of 9th December, offer naloxone-on-release (NOR) to already-randomized participants who have not yet been released and who were assigned to our control group.

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National Naloxone Programme Scotland – naloxone kits issued in 2013/14 and trends in opioid-related deaths

on . Posted in Research

This report presents information on the number of take-home naloxone kits (hereafter referred to as 'kits') issued as part of the national naloxone programme during 2013/14 (and comparisons with 2011/12 and 2012/13). Data are presented separately for kits issued in the community and Kits issued by prisons, prior to prisoner release.

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Deaths Related to Drug Poisoning in England and Wales, 2013

on . Posted in Research

This bulletin presents the latest figures from the Office for National Statistics (ONS) on deaths related to drug poisoning (involving both legal and illegal drugs) and drug misuse (involving illegal drugs) in England and Wales for the last five years (2009 to 2013). Figures from 1993 are available to download, and are discussed in the commentary to provide further context to the latest (2013) data. Figures presented in this bulletin are for deaths registered each year, rather than occurring each year. See the ‘Impact of registration delays on drug-related deaths’ section below for more information. Figures are given by cause of death, sex, age, substance(s) involved, and area of usual residence of the deceased.

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Service Evaluation of Scotland’s National Take-Home Naloxone Programme

on . Posted in Research

The report sets out the context for the development of a national THN programme. It highlights the fact that Scotland has higher rates of drug-related deaths than other parts of the UK and that between 2002-2012 there was an upward trend in the number of drug-related deaths (DRDs) registered in Scotland.

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National Naloxone Programme Scotland – naloxone kits issued in 2012/13 (revision)

on . Posted in Research

This is a revised version of the second annual release of monitoring information from the National Naloxone Programme in Scotland (further background to the national programme is available at Appendix A1.1). This report presents data on the number of ‘take-home’ naloxone kits issued as part of the national programme during 2012/13 (and comparisons with 2011/12). Data are presented separately for kits issued in the community and kits issued by prisons, prior to prisoner release.

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