Take Home Naloxone in the UK

Naloxone (provided under the brand names Prenoxad and Nyxoid in the UK) is a medication used to reverse opioid overdose. Since 2015, this medication has been more widely available in the UK as a ‘take home’ emergency medication.


This website aims to be a hub for information, guidance, news and research on Take Home Naloxone (THN). The main focus is on THN in the UK, although we have included select pieces of information on the supply of naloxone internationally.

PHE Guidance

Updated 18 February 2019
Public Health England have released updated guidance on take home naloxone in the UK, entiled ‘Widening the Availability of Naloxone’. This can be found on the PHE website.
  • Drug services can supply naloxone without a prescription
  • Products that drug services can supply
  • Responsibility for deciding who can supply naloxone
  • People who can be supplied naloxone by a drug service
  • Using naloxone to save a person’s life without their permission
  • Clinical governance in drug treatment services
  • Guidance for hostels, homeless shelters and housing associations
  • Side effects associated with naloxone

Harm Reduction Database Wales: Take Home Naloxone 2015-16

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The supply of ‘Take Home Naloxone’ (THN) was initiated (pilot project) in 2009 as a harm reduction tool used to prevent fatal opioid poisonings, and has since been fully implemented across all health boards in Wales. This report provides data on the training and provision of THN kits from 49 registries across Wales recorded on the Harm Reduction Database Wales (HRD) during the period 1st April 2015 to 31st March 2016.

Stop the deaths

This year the Scottish Drugs Forum  #StopTheDeaths campaign highlights the role we all have in recognising and intervening when a person overdoses.

Overdose is not a rare occurrence and the difference between an overdose and a fatal overdose depends upon the immediate actions of people present at the time. You could save a life by recognising an overdose.  

#StopTheDeaths images © SDF 2021


Ontario looking to make naloxone kits mandatory at high-risk workplaces

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The Ontario government says it has introduced legislation that would require workplaces at high risk for an opioid overdose to have life-saving naloxone kits on site. Some high-risk workplaces listed by the government include construction sites, bars and nightclubs.

Philadelphia Launches ‘Narcan Near Me’ Towers To Combat Overdoses

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Philadelphia has a new tool in its fight against the ongoing opioid crisis. It’s a tower where anyone can get Narcan at a moment’s notice by hitting a few buttons on a touch screen.

Naloxone: Bedfordshire Police pilot scheme to help save lives and counter drug overdoses

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“I think at the moment we’re just going to have a specific trial with a controlled sample of people and then we’ll decide based on the trial how far we want to roll that out. But it’s pleasing that we are one of the forces that’s taking this on,” Bedfordshire’s deputy chief constable, Trevor Rodenhurst said.

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